Antibiotic Susceptibility of Escherichia coli Isolated from Patients with Urinary Tract Infection in Tabriz Hospitals and Medical Centers, Iran

  • Homeira Khaneshpour, * Department of Microbiology, Ahar Branch, Islamic Azad University, Ahar, Iran https://orcid.org/0000-0002-1479-1021
  • Salar Fatemi Department of Microbiology, Ahar Branch, Islamic Azad University, Ahar, Iran
  • Saeed Shokri Department of Microbiology, Ahar Branch, Islamic Azad University, Ahar, Iran
  • Reza Shokri Department of Microbiology, Ahar Branch, Islamic Azad University, Ahar, Iran
Keywords: Escherichia coli, Urinary Tract Infection, Antibiotic Resistance

Abstract

Introduction: Escherichia coli is a common cause of nosocomial infections due to the increasing prevalence of antibiotic use and the development of antibiotic resistance among E. coli strains. The present study investigated the susceptibility and antibiotic resistance patterns of the strains.
Methods: This cross-sectional study was performed on 215 urine samples from hospitals and medical centers of Tabriz during the first six months of 2019 and after identification of E. coli strains using Kirby-Bauer susceptibility and resistance pattern 13 Antibiotics were studied.
Results: Of 215 studied samples, 100 (46.51%) were positive for E.coli infection. The results of antibiogram showed that the highest resistance to ampicillin (69%) and tetracycline (57%) were the most sensitive to amikacin (98%), nitrofurantoin (94%) and tobramycin (94%), respectively. Twenty isolates were resistant to more than 3 classes of antibiotics.
Conclusion: Due to the high level of contamination of specimens isolated from urinary tract infection with E. coli, it is recommended to perform antibiogram testing on the UTI-producing strains before self-administration of antibiotics.

 

ACKNOWLEDGMENTS
Thanks to the assistance of the Islamic Azad University of Ahar, Iran (Microbiology Laboratory).
CONFLICTS OF INTEREST
We declare that we have no financial or nonfinancial conflicts of interest related to the subject matter or materials discussed in the article.
FUNDING
There is no funding for this work.
AUTHORS’ CONTRIBUTIONS
All authors contributed equally to this work.

Author Biography

Homeira Khaneshpour, *, Department of Microbiology, Ahar Branch, Islamic Azad University, Ahar, Iran

khaneshpourhomeira@gmail.com

Published
2019-06-30
Section
Original Article